14.3.3 beta antibody (10R-1096)

Mouse monoclonal 14-3-3 beta antibody

Synonyms Monoclonal 14.3.3 beta antibody, Anti-14-3-3 beta antibody, Tyrosine 3-monocxygenase/tryptopan 5-monooxygenase activation protein antibody, KCIP-1 antibody, HS 1 antibody, beta polypeptide 14 3 3 protein beta/alpha antibody, 14-3-3 beta antibody, Tyrosine 3-monocxygenase/tryptopan 5-monooxygenase activation protein antibody, 14-3-3 beta antibody, Protein kinase C inhibitor protein 1 antibody, 14/3/3 beta antibody, 14.3.3 beta, HS1 antibody, Tyrosine 3 Monooxygenase/Tryptophan 5 Monooxygenase Activation Protein beta Polypeptide antibody, Protein 1054 antibody, 14/3/3 beta, beta polypeptide antibody, GW128 antibody, KCIP 1 antibody, YWHAB antibody, 14-3-3 beta antibody, Brain protein 14 3 3 beta isoform antibody, GW 128 antibody, 14-3-3 beta, KCIP1 antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen 14-3-3 beta antibody was raised in mouse using recombinant human 14-3-3 beta (1-246aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone J2E9
Isotype IgG2a kappa
Source Anti-human 14-3-3 beta antibody, clone J2E9, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human YWHAB protein.
Method of Purification 14-3-3 beta antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1,000-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms,beta, gamma,epsilon, sigma, zeta, tau and theta that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.

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Availability: In stock

Price: €249.33
Size: 100 ul
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