14.3.3 epsilon antibody (10R-1078)

Mouse monoclonal 14-3-3 epsilon antibody

Synonyms Monoclonal 14.3.3 epsilon antibody, Anti-14.3.3 epsilon antibody, YWHAE antibody, 14-3-3 epsilon antibody, 14-3-3 epsilon antibody, 14 3 3E antibody, MDCR antibody, KCIP 1 antibody, 14/3/3 epsilon, MDS antibody, Tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein antibody, 14/3/3 epsilon antibody, FLJ45465 antibody, 14.3.3 epsilon, KCIP-1 antibody, 14-3-3 epsilon antibody, Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide. antibody, Mitochondrial import stimulation factor L subunit antibody, Tyrosine 3/tryptophan 5 -monooxygenase activation protein antibody, 14-3-3 epsilon, Protein kinase C inhibitor protein1 antibody, epsilon polypeptide antibody, KCIP1 antibody, epsilon polypeptide 14 3 3 E antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen 14-3-3 epsilon antibody was raised in mouse using recombinant human 14-3-3 epsilon (1-255aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 5A5
Isotype IgG2a kappa
Source Anti-human 14-3-3 epsilon antibody, clone 5A5, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-3 epsilon protein.
Method of Purification 14-3-3 epsilon antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1,000-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms,beta, gamma,epsilon, sigma, zeta, tau and theta that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.

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Availability: In stock

Price: €249.33
Size: 100 ul
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