41BB ligand protein (His tag) (80R-1143)

Purified recombinant Human 41BB ligand protein

Synonyms CD137L protein, 4 1BB L protein, 4 1BB ligand protein, ILA ligand (TNF related) protein, 4 1BBL protein, TNFSF9 protein, Cd157l protein, Ly63l protein, Cd137l protein, Tumor necrosis factor ligand superfamily member 9 protein, 4-1BBL protein, 4-1BB ligand protein, receptor 4 1BB ligand protein, Tumor necrosis factor (ligand) superfamily member 9., homolog of mouse 4 1BB L protein, homolog of mouse 4 1BBL protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of 41BB ligand protein (His tag) (80R-1143)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 71-254 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTG GLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRL GVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPAGLPSPR SE
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 23.8 kDa (222aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 100mM NaCl, and 20% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance 4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease. Recombinant human 4-1BB ligand, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of 41BB ligand protein (His tag) (80R-1143) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €239.92
Size: 100 ug
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