8-OHdG antibody (20R-3019)

Goat polyclonal 8-OHdG antibody

Synonyms Polyclonal 8-OHdG antibody, Anti-8-OHdG antibody, -OHdG -8 antibody, 8-Hydroxyguanosine antibody, 8-OHdG, -OHdG 8 -OHdG -8, -OHdG 8 antibody
Specificity Reacts with 8-Hydroxydeoxyguanosine (8-OHdG) and 8-Hydroxyguanosine (8-OHG)
Cross Reactivity Human
Applications ELISA, IHC-P
Immunogen 8-OHdG antibody was raised in goat using 8-Hydroxy-2'-deoxyguanosine and 8-hydroxyguanosine as the immunogen

Specifications

Host Goat
Form & Buffer Goat Serum. Supplied in liquid formcontaining 0.01% Thimerosal.

Usage & Assay Information

Usage Recommendations IHC-P: 1:200

Storage & Safety

Storage Store for 1 year at -20 deg C

General Information

Biological Significance 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.

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Availability: In stock

Price: €667.48
Size: 200 ul
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