ACE antibody (10R-A141a)
Mouse monoclonal ACE antibody
Overview
Overview
| Synonyms | Monoclonal ACE antibody, Anti-ACE antibody, Angiotensin Converting Enzyme antibody, CD143 antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | Cat, hamster, monkey, rat |
| Applications | ELISA, ICC, IHC-F, IP, WB |
| Immunogen | ACE antibody was raised in mouse using ACE from human lung as the immunogen. |
Images
Immunohistochemical staining using ACE antibody (10R-A141a)
Mouse anti-ACE antibody staining of rat heart myocardium three weeks after a myocardial infarction
Specifications
| Host | Mouse |
|---|---|
| Clone | 9B9 |
| Isotype | IgG1 |
| Form & Buffer | PBS, pH 7.4, with 150mM NaCl and 0.05% NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Usage Recommendations | ELISA: 1:1,000, ICC: 1:100, IHC-F: 1:1,000, IP: 1:1,000-1:10,000, WB: 1:100 |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. |
General Information
| Biological Significance | Angiotensin I-converting enzyme an exopeptidase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS), which mediates extracellular volume (i.e. that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II. |
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