Adenovirus Fiber antibody (10R-A116b)

Mouse monoclonal Adenovirus Fiber antibody

Synonyms Monoclonal Adenovirus Fiber antibody, Anti-Adenovirus Fiber antibody, Adenovirus Fiber AB4
Specificity Adenovirus
Cross Reactivity Antibody cross-reactivity has not been studied
Applications IF, WB
Immunogen Adenovirus fiber antibody was raised in mouse using UV-irradiated Ad2 virus as the immunogen.

Specifications

Host Mouse
Clone 4D2
Isotype IgG2a kappa
Method of Purification Adenovirus Fiber antibody was purified by Protein A chromatography.
Molecular Weight Mol. wt. 62kDa (monomer) and 180-200kDa (trimer).
Form & Buffer Antibody purified from Ascites fluid by Protein G Chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Adenovirus capsid proteins are synthesized in the cytoplasm and transported to the nucleus for assembly into the virus particles. The three major capsid proteins (hexon, penton base, and fiber) are synthesized late in infection. Fiber plays a crucial role in adenovirus infection by attaching the virus to a specific receptor on the cell surface. Ad2 and Ad5 fibers are proposed to consist of three domains: an N-terminal tail that interacts with penton base, a shaft composed of 22 repeats of a 15 amino acid segment that forms beta-sheet and beta-bends, and a knob at the C-terminus that contains the typespecific antigen and is responsible for binding to the cell surface receptor. It is shown that the fiber of Ad2 is most likely a trimer when found on the viron.

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Availability: In stock

Price: €475.13
Size: 100 ug
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