ADI1 protein (His tag) (80R-2679)
Purified recombinant ADI1 protein (His tag)
|Synonyms||Acireductone dioxygenase 1 protein, APL1 protein, ARD protein, FLJ10913 protein, MTCBP1 protein, HMFT1638 protein, MTCBP-1 protein, SIPL protein, ADI1, ADI 1, ADI-1, ADI 1 protein, ADI-1 protein|
SDS-PAGE analysis of ADI1 protein (His tag) (80R-2679)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-179 aa: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSSMVL AWYMDDAPGD PRQPHRPDPG RPVGLEQLRR LGVLYWKLDA DKYENDPELE KIRRERNYSW MDIITICKDK LPNYEEKIKM FYEEHLHLDD EIRYILDGSG YFDVRDKEDQ WIRIFMEKGD MVTLPAGIYH RFTVDEKNYT KAMRLFVGEP VWTAYNRPAD HFEARGQYVK FLAQTA|
|Grade & Purity||> 90% pure|
|Molecular Weight||25.6 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||ADI1 is an enzyme that belongs to the acireductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Also, it down-regulates cell migration mediated by MMP14. Recombinant human ADI1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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