Adipophilin (C terminal) antibody (20R-2604)

Guinea Pig polyclonal Adipophilin C terminal antibody

Synonyms Polyclonal Adipophilin antibody, Anti Adipophilin antibody
Specificity Human Adipophilin C-terminal
Cross Reactivity To be determined by end-user
Applications IHC, WB
Immunogen Adipophilin (C terminal) antibody was raised in Guinea Pig using synthetic peptide C-terminal aa 423 - 437 of human adipophilin as the immunogen.

Specifications

Host Guinea Pig
Form & Buffer Supplied in liquid form. Contains 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:100, WB: 1:2000

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Adipophilin/ADRP (a member of the PAT family) is a ubiquitous component of lipid droplets. It has been found in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines inducible by etomoxir. Enhanced expression of Adipophilin/ADRP is a useful marker for pathologies characterized by increased lipid droplet accumulation. Such diseases include atheroma, steatosis, obesity and certain cases of liposarcoma. It also seems to be a potent marker for atherosclerosis.

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