AFP antibody (Fab'2) (70R-14344)
Goatpolyclonal AFP antibody (Fab'2)
Overview
Overview
| Synonyms | Polyclonal AFP antibody, Anti-AFP antibody, alpha Fetoprotein antibody, alpha-Fetoprotein antibody, AFP antibody Fab2 fragment, AFP, alpha Fetoprotein, alpha-Fetoprotein, AFP Fab2, AFP Fab'2 |
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| Specificity | Human AFP |
| Immunogen | AFP antibody was raised ingoat using purified Human Alpha Fetoprotein as the immunogen |
Specifications
| Host | Goat |
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| Isotype | IgG |
| Grade & Purity | > 80% pure |
| Method of Purification | AFP antibody was purified using a proprietary two-step fractionation process |
| Form & Buffer | Supplied as a clear, colorless liquid, 0.2 um filtered,in 10 mM Sodium Phosphate, 0.15M Sodium Chloride, pH 7.2 with 0.05% (w/v) Sodium Azide |
| Concentration | 9.85 mg/ml |
Storage & Safety
| Storage | Store at 2-8 deg C |
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General Information
| Biological Significance | Alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
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