AID antibody (biotin) (61R-2066)

Rat monoclonal AID antibody (biotin)

Synonyms Monoclonal AID antibody, Anti-AID antibody, Activation-induced deaminase antibody, Aicda antibody, Aid antibody, Activation-induced cytidine deaminase antibody, Arp2 antibody, Cytidine aminohydrolase antibody
Specificity Human
Cross Reactivity Human, Mouse
Applications IHC, IHC-F, WB

Specifications

Host Rat
Isotype IgG2a kappa
Tag/Conjugate Biotin
Form & Buffer Supplied in an aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 500 ug/ml

Storage & Safety

Storage Store at 2-8 deg C

General Information

Biological Significance AID is a 24 kDa RNA-editing enzyme that converts cytosine into uracil. It plays a critical role during B cell development, specifically in somatic hypermutation (SHM) and immunoglobulin class switch recombination (CSR). Changes in levels of AID expression typically present with disease. For example, mutations in AID are found in Hyper-IgM Syndrome (type 2), a disease form without opportunistic infections, while overexpression correlates with poor prognosis in chronic lymphocytic leukemia/small lymphocytic lymphoma.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price From: Price: €245.40

* Required Fields

Price From: Price: €245.40
Shipping
View Our Distributors