AKR1C1 antibody (70R-10003)
Affinity purified rabbit polyclonal AKR1C1 antibody
Overview
Overview
| Synonyms | Polyclonal AKR1C1 antibody, Anti-AKR1C1 antibody, C9 antibody, MBAB antibody, AKRC-1 antibody, dihydrodiol dehydrogenase 1; 20-alpha, AKRC-1, DDH antibody, H-37 antibody, AKRC 1 antibody, HAKRC antibody, 20-ALPHA-HSD antibody, 3-alpha-hydroxysteroid dehydrogenase antibody, MGC8954 antibody, 2-ALPHA-HSD antibody, AKRC 1, member C1, DD1 antibody, AKR1C1, aldo-keto reductase family 1, DDH1 antibody |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | AKR1C1 antibody was raised in rabbit using the N terminal of AKR1C1 as the immunogen |
| Assay Information | AKR1C1 Blocking Peptide, catalog no. 33R-4926, is also available for use as a blocking control in assays to test for specificity of this AKR1C1 antibody |
Images
Western Blot analysis using AKR1C1 antibody (70R-10003)
Western Blot showing AKR1C1 antibody used at a concentration of 1-2 ug/ml to detect its target protein.
Specifications
| Host | Rabbit |
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| Form & Buffer | Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 0.2-1 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
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