AKR1C1 antibody (70R-12909)
Affinity purified Rabbit polyclonal AKR1C1 antibody
Overview
Overview
| Synonyms | Polyclonal AKR1C1 antibody, Anti-AKR1C1 antibody, AKRC-1 antibody, MBAB antibody, HAKRC antibody, AKR1C1 antibody, H-37 antibody, dihydrodiol dehydrogenase 1/2 antibody, AKRC-1, AKRC 1, high-affinity hepatic bile acid-binding protein antibody, DDH antibody, 2-alpha-HSD antibody, AKR1C1, 20-alpha-hydroxysteroid dehydrogenase antibody, AKRC 1 antibody, 20-alpha-HSD antibody, C9 antibody, MGC8954 antibody, DDH1 antibody, trans-1 2-dihydrobenzene-1 2-diol dehydrogenase antibody, DD1 antibody |
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| Cross Reactivity | Human |
| Applications | ICC, IF, IHC-P, WB |
| Immunogen | AKR1C1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 22 and 248 of AKR1C1 |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | AKR1C1 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 37 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. |
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