alpha 1 Antichymotrypsin protein (30-AC47)
Purified native Human alpha 1 Antichymotrypsin protein
Overview
Overview
| Synonyms | alpha-1-Antichymotrypsin protein, alpha 1 Antichymotrypsin, alpha-1-Antichymotrypsin protein, alpha-1-Antichymotrypsin, A1ACT protein |
|---|---|
| Species | Human |
| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human plasma |
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| Grade & Purity | > 95% pure |
| Molecular Weight | 64 kDa |
| Form & Buffer | Lyophilized from 20mM Tris-HCl, pH 7.4, with 150mM NaCl. Reconstitute in distilled water. |
Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. |
General Information
| Biological Significance | An acute-phase plasma protein found at 45 mg per 100 ml. ACT functions as a specific inhibitor of chymotrypsin-like serine proteases. Clinically, it is elevated in inflammatory conditions, some malignancies, Crohn's disease, ulcerative colitis, and burn injuries. The PSA-ACT complex level is considered a biomarker for prostate cancer. |
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