Amyloid Fibrils antibody (20R-2838)
Rabbit polyclonal Amyloid Fibrils antibody
Overview
Overview
| Synonyms | Polyclonal Amyloid Fibrils antibody, Anti-Amyloid Fibrils antibody, Fibril antibody, Fibrils antibody, Amyloid antibody |
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| Applications | Dot Blot, ELISA, IHC, WB |
| Immunogen | Amyloid Fibrils antibody was raised in Rabbit using fibrils prepared from human AB42 peptide as the immunogen |
Images
Specifications
| Host | Rabbit |
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| Form & Buffer | Supplied in PBS buffer, pH 7.0, 0.09% sodium azide and 50% glycerol |
| Concentration | 500 ug/ml |
Usage & Assay Information
| Usage Recommendations | ELISA: 1-10 ug/ml, IHC: 1-5 ug/ml, Dot Blot: 0.5-1 ug/ml, WB: 1-2 ug/ml |
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General Information
| Biological Significance | Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. They arise from at least 18 inappropriately folded versions of proteins and polypeptides present naturally in the body. These misfolded structures alter their proper configuration such that they erroneously interact with one another or other cell components forming insoluble fibrils. They have been associated with the pathology of more than 20 serious human diseases in that, abnormal accumulation of amyloid fibrils in organs may lead to amyloidosis, and may play a role in various neurodegenerative disorders. |
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