Amyloid P protein (30C-CP1104)

Purified native Human Amyloid P protein

Synonyms SAP protein, Serum Amyloid P Component protein
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human plasma
Grade & Purity > 95% pure
Form & Buffer Supplied liquid in 0.01M TRIS buffer, pH 8.0, containing 0.14M NaCl, 0.01M EDTA and 0.09% NaN3. Sterile filtered through a 0.2um membrane.

Storage & Safety

Storage Store at 4 deg C.
Contaminants None detected by SDS PAGE analysis
Biohazard Information Normal human serum/plasma. Starting material donor tested and certified negative for HIV I & II antibodies, Hepatitis B surface antigen and Hepatitis C antibodies.

General Information

Biological Significance Serum Amyloid P is a 25 kDa pentameric protein which is found in human serum, where it modulates immunological responses and inhibits elastase. It is an important contributor to amyloidosis, where amyloid proteins are deposited in a range of organs, which causes them to function incorrectly. This can lead to a range of different symptoms, depending if the amyloidosis is localized or systematic. Amyloid P usually makes up approximately 14% of the dry mass of amyloid deposits in human organs. The amyloid P component is utilized in clinical diagnostics to locate areas of amyloid build up in a technique called serum amyloid P scintigraphy. Amyloid P has also been suggested as an indicator of liver disease.

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Availability: In stock

Price: €258.73
Size: 250 ug
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