ELISA: 1:10,000- 1:100,000 (50-100 ng of control peptide/well), IHC: 2-20 ug/ml, IF: 2-20 ug/ml, WB: 1-10 ug/ml
Storage & Safety
Storage
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Angiopoietin-2 is a homolog of Angiopoietin-1 (mouse and human Ang-2, 496 AA; ~85% identity) that has recently been identified. It may act an antagonist for Ang-1 and the Tie-2 receptor. Ang-1 and Ang-2 have ~60% sequence homology.
It is prominently expressed in tissues that are in involved in vascular remodeling (ovary, placenta, and uterus).