ANGPTL3 protein (80R-4294)

Purified Recombinant ANGPTL3 protein (His tagged)

Synonyms ANG-5 protein, ANGPT5 protein, ANL3 protein, FHBL2 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis using ANGPTL3 protein (His tag) (80R-4294)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 243-460 aa: MGSSHHHHHH SSGLVPRGSH MPAECTTIYN RGEHTSGMYA IRPSNSQVFH VYCDVISGSP WTLIQHRIDG SQNFNETWEN YKYGFGRLDG EFWLGLEKIY SIVKQSNYVL RIELEDWKDN KHYIEYSFYL GNHETNYTLH LVAITGNVPN AIPENKDLVF STWDHKAKGH FNCPEGYSGG WWWHDECGEN NLNGKYNKPR AKSKPERRRG LSWKSQNGRL YSIKSTKMLI HPTDSESFE
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 27.7 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20 mM Tris-HCl (pH 8.0) containing 10% glycerol
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeat freeze/thaw cycles

General Information

Biological Significance ANGPTL3 also known as Angiopoietin-related protein 3 is a member of the angiopoietin-like family of secreted factors. It is expressed predominantly in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain, and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. Recombinant human ANGPTL3, fused to His-tag at N-terminus, was expressed in E.coli.

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Images

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SDS-PAGE analysis using ANGPTL3 protein (His tag) (80R-4294)



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Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €275.66
Size: 100 ug
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