Annexin A5 protein (30R-1406)
Purified recombinant Human Annexin A5 protein
|Synonyms||Annexin A5, Annexin V protein, Annexin A-5 protein, ANX5 protein, ANX A5 protein, Calphobindin I protein, Annexin A-5, Lipocortin V protein, Annexin 5 protein, Annexin A 5 protein, ENX2 protein, Anchorin CII protein, PAP I protein, PP4 protein, Annexin A 5, Placental anticoagulant protein I., Annexin A5 protein, Endonexin II protein|
Coomassie Blue stained SDS-PAGE of Annexin A5 protein (30R-1406)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-320 amino acids: MAQVLRGTVT DFPGFDERAD AETLRKAMKG LGTDEESILT LLTSRSNAQR QEISAAFKTL FGRDLLDDLK SELTGKFEKL IVALMKPSRL YDAYELKHAL KGAGTNEKVL TEIIASRTPE ELRAIKQVYE EEYGSSLEDD VVGDTSGYYQ RMLVVLLQAN RDPDAGIDEA QVEQDAQALF QAGELKWGTD EEKFITIFGT RSVSHLRKVF DKYMTISGFQ IEETIDRETS GNLEQLLLAV VKSIRSIPAY LAETLYYAMK GAGTDDHTLI RVMVSRSEID LFNIRKEFRK NFATSLYSMI KGDTSGDYKK ALLLLCGEDD|
|Grade & Purity||> 95% pure|
|Molecular Weight||35.9 kDa (320aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Annexin A5, also known as Annexin V, belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin A5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Recombinant Annexin A5 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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