Annexin I antibody (70R-13689)

Affinity purified Rabbit polyclonal Annexin I antibody

Synonyms Polyclonal Annexin I antibody, Anti-Annexin I antibody, Lipo1 antibody, Lipocortin I antibody
Applications IHC-P, WB
Immunogen Annexin I antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human Annexin I as the immunogen

Images

Immunohistochemical staining using Annexin I antibody (70R-13689)

Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification Annexin I antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Annexin I belongs to the annexins family. These proteins are thought to control the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes. In two lipocortins (I and II) a short amino-terminal sequence distinct from the core structure has potential regulatory functions which are dependent on its phosphorylation state. The gene in the mouse encodes a protein of 346 amino acid residues. Mouse Lipo1 gene spans about 17 kb and is divided into 13 exons. Annexin I gene, mapped to 9q11-q22, is located on mouse chromosome 19. Annexin I acts through the formyl peptide receptor on human neutrophils. Peptides derived from the unique N-terminal domain of annexin I serve as FPR ligands and trigger different signaling pathways in a dose-dependent manner.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using Annexin I antibody (70R-13689)</font></div>     | Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using Annexin I antibody (70R-13689)</font></div>     | Western Blot using Hela Cell Lysate

Availability: In stock

Price: €220.86
Size: 100 ug
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