CD14 antibodies (or Cluster of differentiation 14 antibodies) are used to study CD14 a important surface antigen involved in the innate immune response which is preferentially expressed on monocytes/macrophages. It cooperates with other proteins in order to mediate the innate immune response to bacterial lipopolysaccharides.
CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail, the other a soluble form. CD14 recognises the presence of bacterial lipopolysaccharides by acting as a receptor for lipopolysaccharides as well as several other bacterial epitopes. When CD14 binds to lipopolysaccharide it then delivers it to the MD-2/TLR4 complex for neutralization.
CD14 is a key indicator of immune function and CD14 antibodies are commonly used to research immune responses. Fitzgerald Industries offers a wide range of CD14 antibodies from a variety of commonly used host species. Our high quality range of monoclonal and polyclonal CD14 antibodies are highly specific for human CD14 making them the ideal choice for use in immunological procedures such as ELISA, Immunohistochemistry, Western Blot, Flow Cytometry and more.
Some of our most popular CD14 antibodies include:
This mouse monoclonal CD14 antibody is validated for use in Flow Cytometry and IHC applications. It was raised using porcine peripheral blood lymphocytes making it a Porcine CD14 specific antibody.
This rabbit polyclonal CD14 antibody has been affinity purified and is recommended for use in ELISA, Immunohistochemistry and Western Blot.
CD14 antibody (FITC) - This FITC conjugated monoclonal CD14 antibody is ideal for Immunofluorescence applications such as IFA, DFA and FACS. This CD14 antibody is specific for human CD14.
This mouse monoclonal CD14 antibody (clone 5A3) can be used in ELISA, FACS, IHC, and Western blotting and is an Anti-CD14 IgG1. Below is an image of this CD14 in immunohistochemistry of human lymphnode.
Immunohistochemical analysis of paraffin-embedded human
lymphnode, showing membrane localization using CD14 antibody
with DAB staining.
CD14 antibody (biotin) - Another of our popular conjugated CD14 antibodies, this biotinylated CD14 antibody has an attached biotin tag making it ideal for Flow Cytometry applications, or for Streptavidin based detection assays.