TNF alpha antibody

TNF alpha antibodies are commonly used in cancer studies. TNF alpha or Tumor Necrosis Factor Alpha is a cytokine heavily involved in the regulation of immune cells and an array of secondary functions including the regulation of a wide spectrum of biological processes including lipid metabolism, cell proliferation, differentiation, apoptosis and coagulation. This cytokine has also been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer, where it may act as a tumor promoter.

TNF alpha is a well known pro-inflammatory cytokine and although it is an important mediator of the body’s response to infection, when present in excessive concentrations, it is responsible for the destructive inflammatory processes that occur in cases of muscle injury and other stress situations. It also contributes to the development of type 2 diabetes through its effects on insulin resistance and fatty acid metabolism.

As a major element of the immune response as well as its links to several forms of cancer, TNF alpha is widely studied by researchers seeking new drug targets and other therapies. Fitzgerald Industries supplies a wide range of TNF alpha antibodies for research and diagnostic use. Our range of high quality monoclonal and polyclonal TNF alpha antibodies are part of our vast catalog of cytokine antibodies and are the ideal choice for immunological researchers.

Some of our most popular TNF alpha antibodies include:

TNF alpha antibody - This monoclonal TNF alpha antibody clone 2C8 is Protein A purified and highly specific for human TNF alpha. It offers excellent results in ELISA, Immunohistochemistry and Inhibition.

TNF alpha antibody - This affinity purified rabbit polyclonal TNF alpha antibody is excellent for both ELISA and inhibition studies.

TNF alpha antibody (FITC) - This FITC conjugated monoclonal TNF alpha antibody is ideally suited for use in Flow Cytometry applications.

Normal human blood peripheral cells were stimulated with PMA/Ionomycin in the presence of Brefeldin A for 6 hours. Unstimulated (left) or stimulated (right) cells were surface stained with CD3 antibody (PE) and intracellularly stained with TNF alpha antibody (FITC).
Normal human blood peripheral cells were stimulated with PMA/Ionomycin in the presence of Brefeldin A for 6 hours. Unstimulated (left) or stimulated (right) cells were surface stained with CD3 antibody (PE) and intracellularly stained with TNF alpha antibody (FITC).

We also offer TNF alpha antibody (HRP) and TNF alpha antibody (biotin) conjugated TNF alpha antibodies which can be used in ELISA and Flow Cytometry also.