Antitrypsin protein (30R-1218)

Purified recombinant Human Antitrypsin protein

Synonyms Serpin A1 protein, Clade A member 1 protein, Alpha-1 antiproteinase protein, serum trypsin inhibitor, Alpha 1 protease inhibitor protein, Protease inhibitor 1 protein, A1AT protein, Alpha-1 Antitrypsin protein, A1A protein, Alpha 1 antitrypsin protein, Serpin peptidase inhibitor clade A member 1 protein, MGC9222 protein, PRO2275 protein, MGC23330 protein, cysteine proteinase inhibitor protein, SerpinA1 protein, MGC23330 protein, A1AT protein, AAT protein, Antitrypsin protein, PI protein, Serine proteinase inhibitor protein, Alpha 1 antiproteinase protein, alpha1 PI protein, alpha 1 AT protein, PI1 protein, SERP1NA1 protein, alpha1 proteinase inhibitor protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Antitrypsin protein (30R-1218)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 25-418 amino acids: MEDPQGDAAQ KTDTSHHDQD HPTFNKITPN LAEFAFSLYR QLAHQSNSTN IFFSPVSIAT AFAMLSLGTK ADTHDEILEG LNFNLTEIPE AQIHEGFQEL LRTLNQPDSQ LQLTTGNGLF LSEGLKLVDK FLEDVKKLYH SEAFTVNFGD TEEAKKQIND YVEKGTQGKI VDLVKELDRD TVFALVNYIF FKGKWERPFE VKDTEEEDFH VDQVTTVKVP MMKRLGMFNI QHCKKLSSWV LLMKYLGNAT AIFFLPDEGK LQHLENELTH DIITKFLENE DRRSASLHLP KLSITGTYDL KSVLGQLGIT KVFSNGADLS GVTEEAPLKL SKAVHKAVLT IDEKGTEAAG AMFLEAIPMS IPPEVKFNKP FVFLMIDQNT KSPLFMGKVV NPTQK
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 44.4 kDa (395 aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris, pH 7.5, containing 10% glycerol, 1mM DTT, and 2mM EDTA.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Alpha 1 proteinase inhibitor (Antitrypsin) has a characteristic secondary structure of beta sheets and alpha helices. That is a serum glycoprotein synthesized in the liver. It acts as an elastase inhibitor, primarily inhibiting neutrophil elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. Also an increase in Antitrypsin occurs as an acute phase response to tissue necrosis and inflammation. Serum level of Antitrypsin is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis. Recombinant Antitrypsin protein was expressed in E. coli and purified by using conventional chromatography techniques.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Coomassie Blue stained SDS-PAGE of Antitrypsin protein (30R-1218) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €277.55
Size: 100 ug
OR
Shipping
View Our Distributors