APOA1 protein (80R-4196)
Recombinant Mouse APOA1 protein with His tag
Overview
Overview
| Synonyms | Mouse APOA1 protein, Recombinant APOA1 protein, Apolipoprotein A-I protein, Alp-1 protein, apo-AI protein, Apoa-1 protein, apoA-I protein, Brp-14 protein,Ltw-1 protein, Lvtw-1 protein, Sep-1 protein, Sep-2 protein, Sep2 protein, Apolipoprotein AI protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | Control, SDS-PAGE |
Images
Coomassie blue stained SDS-PAGE showing analysis of APOA1 protein(80R-4196)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | 25-264 amino acids of Mouse APOA1 protein: MGSSHHHHHH SSGLVPRGSH MGSDEPQSQW DKVKDFANVY VDAVKDSGRD YVSQFESSSL GQQLNLNLLE NWDTLGSTVS QLQERLGPLT RDFWDNLEKE TDWVRQEMNK DLEEVKQKVQ PYLDEFQKKW KEDVELYRQK VAPLGAELQE SARQKLQELQ GRLSPVAEEF RDRMRTHVDS LRTQLAPHSE QMRESLAQRL AELKSNPTLN EYHTRAKTHL KTLGEKARPA LEDLRHSLMP MLETLKTQVQ SVIDKASETL TAQ |
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| Expression System | E.coli |
| Grade & Purity | > 90% pure |
| Molecular Weight | 30.3 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in PBS (pH 7.4) containing 20% glycerol and 1mM DTT |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term. For long term storage, aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles. |
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General Information
| Biological Significance | Apoa1 also known as Apolipoprotein A-I, is the major protein component of high density lipoprotein (HDL) in plasma. This protein promotes cholesterol efflux from tissues to the liver for excretion. And it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apoa1 are associated with HDL deficiency including Tangier disease. Recombinant mouse Apoa1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques |
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