ApoB protein (30-AA34)
Purified native Human ApoB protein
Overview
Overview
| Synonyms | Apolipoprotein B protein, Apo-B protein, Apo B protein, Low Density lipoprotein protein, LDL protein |
|---|---|
| Species | Human |
| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human plasma |
|---|---|
| Grade & Purity | > 95% pure |
| Molecular Weight | 550 kDa |
| Form & Buffer | Lyophilized from 10 mM Na deoxycholate, pH 10.0, with 50 mM Na2CO3 and 50 mM NaCl |
Storage & Safety
| Storage | 4°C shipping. Upon receipt store at -20°C. |
|---|---|
| Contaminants | Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. |
General Information
| Biological Significance | Apolipoprotein B is the dominant protein constituent of LDL. The concentration of Apo B in normal plasma is 90 mg per 100 ml. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and modulator of enzymatic reactions, manage export of lipids out of cells and direct lipids to target organs. Apo B levels are positively correlated with the risk of coronary disease. Apo B levels may be a more sensitive predictor of cardiovascular risk than LDL levels and do not involve fasting for accurate measurement. Two forms of Apo B exist: Apo B-100 and Apo B-48. The first is found in VLDL and LDL and is produced by the liver. The second is found in chylomicrons and originates in the intestine. . |
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