Polyclonal ApoC-III antibody, Anti-ApoC-III antibody, Apo C III antibody, Apolipoprotein C III antibody, ApoC3 antibody, Apo CIII antibody, Apo-CIII antibody
Specificity
Human apolipoprotein C-III
Cross Reactivity
To be determined by end-user
Applications
ELISA, IHC, IP, WB
Immunogen
ApoC-III antibody was raised in goat using produced from apolipoprotein type C-III derived from human plasma as the immunogen.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
General Information
Biological Significance
Apolipoprotein C-III is a very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to inhibit hepatic uptake of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.