ApoC-III protein (30-AA28)
Purified native Human ApoC-III protein
Overview
Overview
| Synonyms | Apolipoprotein C III protein, Apo CIII protein, Apo C III protein, ApoC3 protein, Apo-CIII protein |
|---|---|
| Species | Human |
| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human plasma |
|---|---|
| Grade & Purity | > 95% pure |
| Molecular Weight | 8.75 kDa |
| Form & Buffer | Supplied as a liquid in 10mM NH4HCO3, pH 7.4. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Storage & Safety
| Storage | Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles. |
|---|---|
| Biohazard Information | Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. |
General Information
| Biological Significance | Apo CIII inhibits the activation of lipoprotein lipase by Apo CII. Reduced levels of Apo CIII result in higher fatty acid uptake from plasma triglycerides into adipose tissue. Thus, Apo CIII is a potential target for treatment of obesity and insulin resistance. The normal plasma concentration of Apo CIII is 8-15 mg per 100 ml. |
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