APP antibody (20-AG72)

Goat polyclonal APP antibody

Synonyms Polyclonal APP antibody, Anti-APP antibody, Amyloid Precursor Protein antibody
Specificity Human APP
Cross Reactivity To be determined by end-user
Applications ELISA, WB
Immunogen APP antibody was raised in goat using a peptide; RGRTSSKELAI, as the immunogen.

Specifications

Host Goat
Form & Buffer Neat serum with no preservatives.

Usage & Assay Information

Usage Recommendations ELISA: >1:5,000, WB: >1:3,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The amyloid precursor protein (APP) is a large membrane protein whose N-terminus projects into the extracellular space. In Alzheimer's disease (AD), this protein is broken down and releases the Ab peptide that is found in senile plaques and vessels. A frameshift mutant of APP has been found that results from a GA dinucleotide deletion which results in a frameshift mutation that gives rise to a truncated APP with a unique C-terminus. The role of the amyloid precursor protein frameshift mutant (APPFM) in AD is currently unknown. These abnormal proteins may accumulate and lead to cellular disturbances and neuronal degeneration.

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Availability: In stock

Price: €211.69
Size: 100 ul
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