APP antibody (70R-13905)

Affinity purified Goat polyclonal APP antibody

Synonyms Polyclonal APP antibody, Anti-APP antibody, Amyloid Precursor Protein antibody, APP C-terminus antibody
Applications IHC-P, WB
Immunogen APP antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human APP, identical to the related Rabbit and rat sequence as the immunogen

Images

Immunohistochemical staining using APP antibody (70R-13905)

Immunohistochemistry of paraffin-embedded section of Rat Brain Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification APP antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid (ABeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using APP antibody (70R-13905)</font></div>     | Immunohistochemistry of paraffin-embedded section of Rat Brain Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using APP antibody (70R-13905)</font></div>     | Western Blot using Rat Brain Tissue Lysate

Availability: In stock

Price: €220.86
Size: 100 ug
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