ARFGAP3 antibody (70R-10382)
Affinity purified rabbit polyclonal ARFGAP3 antibody
Overview
Overview
| Synonyms | Polyclonal ARFGAP3 antibody, Anti-ARFGAP3 antibody, ADP-ribosylation factor GTPase activating protein 3 antibody, ARFGAP3, ARFGAP1 antibody, ARFGAP 3 antibody, ARFGAP-3 antibody, ARFGAP 3, FLJ45618 antibody, ARFGAP-3 |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | ARFGAP3 antibody was raised in rabbit using the N terminal of ARFGAP3 as the immunogen |
| Assay Information | ARFGAP3 Blocking Peptide, catalog no. 33R-10325, is also available for use as a blocking control in assays to test for specificity of this ARFGAP3 antibody |
Images
Western Blot analysis using ARFGAP3 antibody (70R-10382)
Western Blot showing ARFGAP3 antibody used at a concentration of 1 ug/ml against 721_B Cell Lysate
Specifications
| Host | Rabbit |
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| Form & Buffer | Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. |
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