ATF2 antibody (20-AS62)
Sheep polyclonal ATF2 antibody
Overview
Overview
| Synonyms | Polyclonal ATF2 antibody, Anti-ATF2 antibody, ATF-2 antibody, ATF2, ATF 2 antibody, Activating Transcription Factor 2 antibody, ATF 2 antibody, ATF-2, ATF-2 antibody, ATF 2 |
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| Cross Reactivity | To be determined by end-user |
| Applications | User optimized |
| Immunogen | ATF2 antibody was raised in Sheep using ATF-2; N-terminal fragment GST-fusion protein as the immunogen. |
Specifications
| Host | Sheep |
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| Method of Purification | Protein G affinity chromatography |
| Form & Buffer | Protein G purified and supplied in PBS, pH 7.5, with no preservatives added. |
| Concentration | Typically 1-5 mg/ml |
Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles. |
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General Information
| Biological Significance | ATF2 is a tTranscriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex. |
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