Anthrax protective Antigen (30R-AA014)
Purified recombinant Bacillus Anthrax protective Antigen
Overview
Overview
| Synonyms | Bacillus Anthracis Protein, Recombinant B Anthracis , Anthrax Protein, Bacillus Anthrax protective Antigen Recombinant Protein |
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| Species | Viral |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Molecular Weight | 83 kDa |
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| Form & Buffer | Lyophilized from 50mM NaCl, 5mM HEPES, pH 7.5. |
Storage & Safety
| Storage | Store at 4 deg C. |
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General Information
| Biological Significance | One of the three protein components of Anthrax toxin, protective antigen (PA) is the central moiety that mediates the entry of lethal factor and edema factor into the target cell. PA binds to the cell surface via a type I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor. After proteolytic activation to a 63 kDa fragment, PA self-associates to form a heptameric cation-selective, voltage-gated membrane channel. |
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