Bax antibody (10R-6622)

Mouse monoclonal Bax antibody

Synonyms Monoclonal Bax antibody, Anti-Bax antibody, Bcl-2–associated X protein antibody
Specificity Mouse, Rat, Monkey, Human
Applications FC, Functional Assay, IHC, IP, WB
Assay Information A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest

Specifications

Host Mouse
Clone 6A7
Isotype IgG1 kappa
Method of Purification Bax antibody was purified by affinity chromatography.
Form & Buffer Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations FC: = 0.5 ug/test

Storage & Safety

Storage Store at 2-8 deg C. Do not freeze. Protect from light.

General Information

Biological Significance The 6A7 antibody reacts with mouse, rat, monkey and human Bax. The 6A7 antibody shows no cross-reaction with Bcl-2 or Bcl-xL proteins. Bcl-2, Bax, and Bcl-xL are members of a protein family that regulates apoptosis while several family members including Bcl-2 and Bcl-xL inhibit apoptosis, overexpression of Bax promotes programmed cell death. A human Bax protein peptide sequence, aa 12-24, was used as immunogen.

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Price From: Price: €134.97
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