Bcl2 antibody (10R-8483)

Mouse monoclonal Bcl2 antibody

Synonyms Monoclonal Bcl2 antibody, Anti-Bcl2 antibody, BCL2 antibody, Bcl 2 antibody, B-cell CLL/lymphoma 2 antibody, apoptosis regulator Bcl-2 antibody, apoptosis regulator Bcl-2 protein antibody, B cell leukemia/lymphoma 2 antibody, B-cell leukemia/lymphoma 2 antibody, B cell lymphoma 2 associated oncogene antibody, B-cell lymphoma protein 2 antibody, Bcl-2 antibody, BCL2B-cell CLL/lymphoma 2 antibody, Bcl2-like protein antibody, BOS_22233 antibody, mitochondrial B-cell CLL/lymphoma 2 antibody, PCKBCL2 antibody, PPP1R50 antibody, protein phosphatase 1 antibody, regulatory subunit 50 antibody, xbcl2 antibody, xBcl-2 antibody, zBlp2 antibody
Cross Reactivity Human
Applications ELISA, IP, WB
Immunogen Bcl2 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-Bcl-2) as the immunogen

Images

Western Blot analysis using Bcl 2 antibody (10R-8483)

Specifications

Host Mouse
Clone 11C5
Isotype IgG2a kappa
Method of Purification Bcl2 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1: 2000, IP: 0.5 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Bcl2 (B-cell lymphoma 2) family govern mitochondrial outer membrane permeabilization (MOMP) and can be either pro-apoptotic (Bax, BAD, Bak, Bid and Bok) or anti-apoptotic (Bcl-2, Bcl-xL, and Bcl-w). The mitochondrial release of cytochrome c through anion channel is regulated by Bcl-2 and Bcl-xL. The Bcl-2 family of proteins are key regulators of many signals leading to caspase, which when activated cause cellular destruction by cleaving a range of vital cellular substrates. The members of the Bcl-2 family share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH) domains (named BH1, BH2, BH3 and BH4).

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using Bcl 2 antibody (10R-8483)

Availability: In stock

Price: €241.31
Size: 100 ul
OR
Shipping
View Our Distributors