Beta 2 Microglobulin antibody (70R-7564)

Affinity purified Goat polyclonal Beta 2 Microglobulin antibody

Synonyms Polyclonal Beta 2 Microglobulin antibody, Anti-Beta 2 Microglobulin antibody, Beta chain of mhc class 1 proteins antibody, Beta Microglobulin 2, Beta Microglobulin 2 antibody, Beta Microglobulin -2, Beta 2 microglobulin precursor antibody, Hdcma22p antibody, B2M antibody, Beta Microglobulin -2 antibody, Beta 2 Microglobulin
Specificity Beta 2 Microglobulin antibody was raised against Human Beta-2-Microglobulin.
Applications User optimized
Immunogen Antibody raised in goat using Human beta-2-microglobulin

Specifications

Host Goat
Source Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian.
Grade & Purity > 95% pure
Method of Purification Affinity purified using solid phase Human beta-2-Microglobulin
Form & Buffer Clear, colorless liquid, 0.2 um filtered, containing 10 mM Sodium Phosphate, 0.15 M Sodium Chloride and 0.05% (w/v) Sodium Azide. Protease/IgG free.
Concentration >4.5 mg/ml

Usage & Assay Information

Usage Recommendations The optimal working dilution should be determined by the end user

Storage & Safety

Storage Store at 2-8 deg C.

General Information

Biological Significance Beta 2 Microglobulin is a low molecular weight protein with sequence homology to immunoglobulins. As a portion of the HLA complex this protein is an important cell-surface structure. Under normal conditions Beta 2 Microglobulin is synthesized and shed by many cells, particularly lymphocytes, and is detectable in the circulation of normal individuals. Because of its small size it is normally filtered readily at the glomerulus and is catabolized by proximal tubular cells of the kidney. Impaired renal function and hyperproduction of Beta 2 Microglobulin are both associated with increased serum levels. A function for Beta 2 Microglobulin as a modulator of lymphocyte surface and as a potential regulator of the immune system is proposed.

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Availability: In stock

Price: €230.67
Size: 1 mg
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