beta Amyloid antibody (70R-10624)
Affinity purified Chicken polyclonal beta Amyloid antibody
Overview
Overview
| Synonyms | Polyclonal beta Amyloid antibody, Anti-beta Amyloid antibody, beta Amyloid N Terminus antibody, APP-A4 antibody, Ab antibody, Alzheimer Precursor Protein A4 antibody, Abeta antibody, Amyloid Plaque antibody, Amyloid beta antibody |
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| Applications | User optimized |
| Immunogen | beta Amyloid antibody was raised in Chicken using a synthetic peptide (corresponding to DAE FRH DSG YEV HHQ KL, residues #1-17 of the amyloid beta-peptide) coupled to keyhole limpet hemocyanin (KLH) as the immunogen. |
Images
Immunohistochemical staining using beta Amyloid antibody (70R-10624)
beta Amyloid positive “neuritic plaque” in cerebral cortex as seen in a post-mortum specimen taken from an Alzheimer’s disease patient. Picture courtesy of Dr. Randy Woltjer, Oregon Health & Sciences University.
Specifications
| Host | Chicken |
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| Method of Purification | beta Amyloid antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in liquid form in 10 mM PBS buffer, pH 7.2, with 0.02% sodium azide added as a preservative. |
| Concentration | 100 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. Protect from light. |
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General Information
| Biological Significance | Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. Alzheimer’s diseased brain tissue is characterised by an abundance of neurofibrillary tangles, neuropil threads and abnormal neuritis in senile plaques. Neurofibrillary tangles represent dense accumulations of ultrastructurally distinct paired helical filaments whose major component is a microtubule-associated tau protein. |
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