Betacellulin protein (30R-AB028)

Purified recombinant Human Betacellulin protein

Synonyms BTC protein, beta Cellulin protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of Betacellulin protein corresponding to amino acids DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 9 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse Balb/3T3 cells is approximately 0.05 ng/ml, corresponding to a specific activity of approximately 2 x 10^7units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.

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Availability: In stock

Price: €211.69
Size: 20 ug
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