BID antibody (10R-1121)

Mouse monoclonal BID antibody

Synonyms Monoclonal BID antibody, Anti-BID antibody, p22 BID. antibody, BID isoform L(2) antibody, p13 BID antibody, BH3 interacting domain death agonist isoform 2 Apoptotic death agonist antibody, BH3 interacting domain death agonist p15 antibody, MGC15319 antibody, BID isoform ES(1b) antibody, BID antibody, BH3 interacting domain death agonist isoform 2 antibody, HGNC:1050 antibody, MGC42355 antibody, p11 BID antibody, BH3 interacting domain death agonist p13 antibody, Human BID coding sequence antibody, FP497 antibody, OTTHUMP00000196197 antibody, p15 BID antibody, BH3 interacting domain death agonist p11 antibody, Apoptotic death agonist BID antibody, BH3 interacting domain death agonist antibody, Desmocollin type 4 antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen BID antibody was raised in mouse using recombinant human BID (1-195aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 4D3
Isotype IgG1 kappa
Source Anti-human BID antibody, clone 4D3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human BID protein.
Method of Purification BID antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1,000-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases.

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Availability: In stock

Price: €249.33
Size: 100 ul
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