Biliverdin reductase B protein (30R-1221)
Purified recombinant Human Biliverdin reductase B protein
|Synonyms||Biliverdin IX beta reductase protein, FLR protein, MGC117413 protein, Flavin reductase (NADPH) protein, Flavin reductase protein, Green heme binding protein protein, MGC117413 protein, BVRB protein, BLVRB protein, FR protein, SDR43U1 protein, NADPH flavin reductase., GHBP protein, NADPH dependent diaphorase protein, Biliverdin reductase B protein, BVR B protein|
Coomassie Blue stained SDS-PAGE of Biliverdin reductase B protein (30R-1221)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-206 amino acids: MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ|
|Grade & Purity||> 95% pure|
|Molecular Weight||22.1 kDa (206 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 8.5, containing 10% glycerol, and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Biliverdin reductase B (BLVRB) is an enzyme that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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