BIP protein (30R-1212)

Purified recombinant Human BIP protein

Synonyms Binding immunoglobulin protein protein, Heat Shock 70kDa Protein 5 protein, glucose-regulated protein 78kD protein, Immunoglobulin Heavy Chain Binding Protein., Endoplasmic reticulum lumenal Ca2+ binding protein grp78 protein, GRP78 protein, BIP protein, HSPA 5 protein, Binding immunoglobulin protein 78 kDa glucose regulated protein protein, HSPA5 protein, MIF2 protein, heat shock 70kDa protein 5 protein, GRP78 protein, FLJ26106 protein, GRP 78 protein, Glucose Regulated Protein 78kDa protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of BIP protein (30R-1212)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 20-650 amino acids: MEEDKKEDVG TVVGIDLGTT YSCVGVFKNG RVEIIANDQG NRITPSYVAF TPEGERLIGD AAKNQLTSNP ENTVFDAKRL IGRTWNDPSV QQDIKFLPFK VVEKKTKPYI QVDIGGGQTK TFAPEEISAM VLTKMKETAE AYLGKKVTHA VVTVPAYFND AQRQATKDAG TIAGLNVMRI INEPTAAAIA YGLDKREGEK NILVFDLGGG TFDVSLLTID NGVFEVVATN GDTHLGGEDF DQRVMEHFIK LYKKKTGKDV RKDNRAVQKL RREVEKAKRA LSSQHQARIE IESFYEGEDF SETLTRAKFE ELNMDLFRST MKPVQKVLED SDLKKSDIDE IVLVGGSTRI PKIQQLVKEF FNGKEPSRGI NPDEAVAYGA AVQAGVLSGD QDTGDLVLLD VCPLTLGIET VGGVMTKLIP RNTVVPTKKS QIFSTASDNQ PTVTIKVYEG ERPLTKDNHL LGTFDLTGIP PAPRGVPQIE VTFEIDVNGI LRVTAEDKGT GNKNKITITN DQNRLTPEEI ERMVNDAEKF AEEDKKLKER IDTRNELESY AYSLKNQIGD KEKLGGKLSS EDKETMEKAV EEKIEWLESH QDADIEDFKA KKKELEEIVQ PIISKLYGSA GPPPTGEEDT AELEHHHHHH
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 71 kDa (640 aa)
Form & Buffer Supplied as a liquid in 20mM Tris, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Binding immunoglobulin protein (BiP) belongs to the family of ~70 kDa heat shock proteins (HSP 70). It is a stress response protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding as well as for the maintenance of cell homeostasis and the prevention of apoptosis. Recombinant human BIP protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of BIP protein (30R-1212) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €371.64
Size: 100 ug
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