BLyS protein (His tag) (80R-1037)
Purified recombinant Human BLyS protein
|Synonyms||TALL1 protein, TNFSF13B protein, B lymphocyte stimulator protein, ZTNF4 protein, THANK protein, B-cell activating factor protein, CD257 protein, B lymphocyte stimulator, BlyS protein, TNFSF20 protein, BAFF protein|
Coomassie Blue stained SDS-PAGE of BLyS protein (His tag) (80R-1037)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||49-162 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAV QGPEETVTQD CLQLIADSET PTIQKGSYTF VPWLLSFKRG SALEEKENKI LVKETGYFFI YGQVLYTDKT YAMGHLIQRK KVHVFGDELS LVTLFRCIQN MPETLPNNSC YSAGIAKLEE GDELQLAIPR ENAQISLDGD VTFFGALKLL|
|Grade & Purity||> 95% pure|
|Molecular Weight||21 kDa (190 aa)|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 8.0, containing 5mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||B lymphocyte stimulator (BLyS),a member of the tumor necrosis factor (TNF) superfamily of cytokines, induces B-cell proliferation and immunoglobulin secretion and is a key regulator of peripheral B-cell populations in vivo.. BLyS is made by immune-cells called monocytes and macrophages. When monocytes and macrophages are activated, BLyS is released and binds to a receptor found only on B cells. Recombinant human BLyS, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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