BM40 protein (30R-3210)
Purified recombinant BM40 protein
Overview
Overview
| Synonyms | Basement membrane 40 protein, BM 40 protein, Osteonectin protein, ON protein, Secreted acidic and rich in cysteine protein, SPARC protein, BM 40 protein, BM-40 protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | ELISA, SDS-PAGE, WB |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 90% pure |
| Molecular Weight | 58 kDa |
| Form & Buffer | Supplied in liquid form in PBS buffer with 20 mM GSH |
Storage & Safety
| Storage | Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles |
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General Information
| Biological Significance | BM40 appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity. |
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