BMPR2 antibody (70R-12665)
Affinity purified Rabbit polyclonal BMPR2 antibody
Overview
Overview
| Synonyms | Polyclonal BMPR2 antibody, Anti-BMPR2 antibody, bone morphogenetic protein receptor type II (serine/threonine kinase) antibody, type II receptor for bone morphogenetic protein-4 antibody, BMPR2 antibody, BMPR 2 antibody, FLJ41585 antibody, bone morphogenetic protein receptor type-2 antibody, BMPR-2 antibody, T-ALK antibody, PPH1 antibody, BMPR-2, BMPR3 antibody, BMR2 antibody, FLJ76945 antibody, BMPR-II antibody, BMP type II receptor antibody, type II activin receptor-like kinase antibody, BMP type-2 receptor antibody, BMPR 2, BRK-3 antibody, BMPR-2 antibody, bone morphogenetic protein receptor type II antibody, BMPR2 |
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| Cross Reactivity | Human, Mouse |
| Applications | WB |
| Immunogen | BMPR2 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 667 and 951 of BMPR2 |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | BMPR2 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 115 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.89 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. |
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