Butyrophilin antibody (20R-2588)

Guinea Pig polyclonal Butyrophilin antibody

Synonyms Polyclonal Butyrophilin antibody, Anti Butyrophilin antibody
Specificity Bovine Butyrophilin
Cross Reactivity Rat, Mouse
Applications IHC, WB
Immunogen Butyrophilin antibody was raised in Guinea Pig using Butyrophilin purified from bovine milk fat globule membrane as the immunogen.

Specifications

Host Guinea Pig
Form & Buffer Supplied in liquid form. Contains 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IF: 1:100-200, WB: 1:2000

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Butyrophilin (Btn) genes constitute a subgroup of at least 10 genes in the Ig superfamily identified in human, mouse, cow, goat and other species. The eponymous Btn gene (BTN1A1 in humans; Btn1a1 in mouse) is highly expressed in the secretory epithelium of the mammary gland during lactation. Other homologues are predominantly expressed in skeletal muscle and the intestine and erythroid cells. In contrast, BTN2A1 and 2 and BTN3A1, 2, and 3 are widely expressed in many tissues, suggesting that the structural domains of Btn proteins may have both universal and tissue-specific functions.

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