c-Jun antibody (20R-1615)

Rabbit polyclonal c Jun antibody

Synonyms Polyclonal c Jun antibody, Anti-c Jun antibody, Phospho-c-Jun antibody, Ser73 antibody
Specificity The Phospho-c-Jun (Ser73) antibody detects only activated c-Jun when phosphorylated at Ser73. It does not react with non-phosphorylated c-Jun.
Cross Reactivity Human, Mouse, Rat
Applications IHC, WB

Specifications

Host Rabbit
Method of Purification c Jun (Ser73) antibody was purified by affinity purification.
Form & Buffer Supplied in PBS buffer, pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations IHC: 10-20 ug/ml, WB: 1 ug/ml

Storage & Safety

Storage Store at -20 deg C. For long-term storage, aliquot and freeze at -70 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance c Jun is a component of the transcription factor AP 1 that binds and activates transcription at TRE/AP 1 elements. The transcriptional activity of c Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals, such as growth factors and UV irradiation, stimulate phosphorylation of c Jun at Ser63/73 and activate c Jun dependent transcription. The MAP kinase homologue, SAPK/JNK, binds to the N terminal region of c Jun and phosphorylates c Jun at Ser63/73.

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Availability: In stock

Price: €511.25
Size: 100 ug
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