c-Jun antibody (20R-1709)

Rabbit polyclonal c Jun antibody

Synonyms Polyclonal c Jun antibody, Anti-c Jun antibody, c-Jun antibody, AP-1 antibody, AP1 antibody, JUN antibody
Specificity The antibody only recognizes c-Jun, and will not detect the endogenous levels of Jun B or Jun D.
Cross Reactivity Human, Mouse, Rat
Applications IHC, WB

Specifications

Host Rabbit
Method of Purification c Jun antibody was purified by affinity purification.
Form & Buffer Supplied in PBS buffer, pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations IHC: 20-40 ug/ml, WB: 0.5-2 ug/ml

Storage & Safety

Storage Store at -20 deg C. For long-term storage, aliquot and freeze at -70 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Extracellular stimuli such as growth factors and UV irradiation stimulate phosphorylation of c Jun at Ser63/73 and activate c Jun dependent transcription. Mutation at Ser63/73 renders c Jun nonresponsive to mitogenic and stress induced signaling pathways. JNK (c jun N terminal Kinase) binds to the N terminal region of c Jun and phosphorylates c Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activate c Jun.

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Availability: In stock

Price: €486.71
Size: 100 ug
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