c-Jun antibody was raised in Rabbit using the peptide sequence around phosphorylation site of serine 73 (L-A-S(p)-P-E) derived from Human c-Jun as the immunogen.
Immunohistochemical staining using c-Jun antibody (20R-1879)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Jun (Phospho-Ser73) antibody (left) or the same antibody preincubated with with blocking peptide (right)
c-Jun antibody
Immunohistochemical staining using c-Jun antibody (20R-1879)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Jun (Phospho-Ser73) antibody (left) or the same antibody preincubated with with blocking peptide (right)
Western Blot analysis using c-Jun antibody (20R-1879)
Western Blot analysis of extracts from PC14 cells untreated or treated with EGF using c-Jun (Phospho-Ser73) antibody
Specifications
Host
Rabbit
Method of Purification
c-Jun antibody was purified by immunoaffinity chromatography.
Form & Buffer
Supplied in liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl, 0.02% sodium azide and 50% glycerol.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
c-Jun is the name of a gene and protein that, in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the JNK pathway but has also a phosphorylation-independent function. c-Jun knockout is lethal, but transgenic animals with a mutated c-Jun that cannot be phosphorylated (termed c-JunAA) can survive.