c-Jun antibody (20R-1890)
Rabbit polyclonal c-Jun antibody
Overview
Overview
| Synonyms | Polyclonal c-Jun antibody, Anti-c-Jun antibody, Phospho Tyr170 antibody, JUN antibody, AP1 antibody |
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| Cross Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Immunogen | c-Jun antibody was raised in Rabbit using the peptide sequence around phosphorylation site of tyrosine 170 (P-V-Y(p)-A-N) derived from Human c-Jun as the immunogen. |
Images
Western Blot analysis using c-Jun antibody (20R-1890)
Western Blot analysis of extracts from Hela and 293 cells untreated or treated with EGF using c-Jun (Phospho-Tyr170) antibody
Specifications
| Host | Rabbit |
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| Method of Purification | c-Jun antibody was purified by immunoaffinity chromatography. |
| Form & Buffer | Supplied in liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 1:500-1:1000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | c-Jun is the name of a gene and protein that, in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the JNK pathway but has also a phosphorylation-independent function. c-Jun knockout is lethal, but transgenic animals with a mutated c-Jun that cannot be phosphorylated (termed c-JunAA) can survive. |
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