C3aR antibody (70R-12362)
Rabbit polyclonal C3aR antibody
Overview
Overview
| Synonyms | Polyclonal C3aR antibody, anti-C3aR antibody, C3AR antibody, C3a receptor-like antibody, C3a anaphylatoxin chemotactic receptor antibody, CaR-3 antibody, CaR 3 antibody, C3aR, CaR-3, C3a anaphylatoxin chemotactic antibody, CaR 3, C3a-R antibody |
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| Cross Reactivity | Human |
| Applications | FC |
| Immunogen | C3aR antibody was raised in Rabbit using E coli expressed human C3aR (aa 161-332) as the immunogen. |
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | C3aR antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in PBS buffer containing 50% glycerol, 1% BSA, and 0.02% thimerosal |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | C3a is an anaphylatoxin generated through activation of the complement C3. C3a is a potent chemoattractant for phagocytes, and it stimulates chemotaxis and other leukocyte functions. C3a binds to eosinophils, basophils, neutrophils, and differentiated U937 cells, that all express receptors for C3a on their cell surface. The C3a receptor has been cloned and shown to be a G protein-coupled receptor with seven putative transmembrane domains. This receptor is characterized for its large extracellular loop between the fourth and fifth transmembrane domains. The loop can be readily detected using the rabbit anti-C3a receptor antibody. |
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