C5a protein (His tag) (80R-2544)
Purified recombinant Mouse C5a protein (His-Tag)
Overview
Overview
| Synonyms | Ca 5, C5a, Ca-5, Complement Fragments C5a protein, Ca 5 protein, Ca-5 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
Specifications
| Expression System | E.coli |
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| Method of Purification | C5a protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 9 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in lyophilized form with no additives |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | <0.1 ng/ug |
General Information
| Biological Significance | Complement C5a is a 77-amino acid peptide generated during complement activation from the alpha-chain of complement C5. Mouse C5a shares 60% and 82% amino acid sequence identity to human and rat C5a, respectively. C5a binds to a signaling G-protein coupled receptor, inducing neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells. |
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