CA 15-3 antibody (10-1145)
Mouse monoclonal CA 15-3 antibody
Overview
Overview
| Synonyms | Monoclonal CA 15-3 antibody, Anti-CA 15-3 antibody CA 15 3, CA 15 3 antibody, CA 15-3 antibody, CA 153 antibody, CA 15-3, Breast Tumor antibody, Cancer Antigen 15-3 antibody |
|---|---|
| Specificity | Human CA15-3 |
| Applications | ELISA, Immunoassays |
| Immunogen | CA 15-3 antibody was raised in Mouse using CA 15-3 antigen from human cell line as the immunogen |
| Assay Information | 10-1145 can be used in ELISA as a capture antibody in conjunction with 10-1144 as the detection antibody |
Specifications
| Host | Mouse |
|---|---|
| Clone | M12147 |
| Isotype | IgG2b kappa |
| Grade & Purity | > 90% pure |
| Method of Purification | CA 15-3 antibody was purified by Protein G chromatography |
| Form & Buffer | Supplied in liquid form in Phosphate Buffer Saline, pH 7.4 (no preservative added) |
Storage & Safety
| Storage | Store at 2-8 deg C for short term storage. Aliquot and store at -15 deg C for long term storage. |
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General Information
| Biological Significance | CA 15-3 (also known as MUC1) is the most widely used serum marker in breast cancer. MUC1 is a large transmembrane glycoprotein which is frequently overexpressed and aberrantly glycosylated in cancer. Physiologically, MUC1 appears to play a role in cell adhesion and the high levels present in cancer may be causally involved in metastasis. At present the main uses of CA 15-3 are in preclinically detecting recurrent breast cancer and monitoring the treatment of patients with advanced breast cancer. |
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CA 15-3 antibody
Mouse monoclonal CA 15-3 antibody