CA 15-3 antibody (10-1145)

Mouse monoclonal CA 15-3 antibody

Synonyms Monoclonal CA 15-3 antibody, Anti-CA 15-3 antibody CA 15 3, CA 15 3 antibody, CA 15-3 antibody, CA 153 antibody, CA 15-3, Breast Tumor antibody, Cancer Antigen 15-3 antibody
Specificity Human CA15-3
Applications ELISA, Immunoassays
Immunogen CA 15-3 antibody was raised in Mouse using CA 15-3 antigen from human cell line as the immunogen
Assay Information 10-1145 can be used in ELISA as a capture antibody in conjunction with 10-1144 as the detection antibody

Specifications

Host Mouse
Clone M12147
Isotype IgG2b kappa
Grade & Purity > 90% pure
Method of Purification CA 15-3 antibody was purified by Protein G chromatography
Form & Buffer Supplied in liquid form in Phosphate Buffer Saline, pH 7.4 (no preservative added)

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -15 deg C for long term storage.

General Information

Biological Significance CA 15-3 (also known as MUC1) is the most widely used serum marker in breast cancer. MUC1 is a large transmembrane glycoprotein which is frequently overexpressed and aberrantly glycosylated in cancer. Physiologically, MUC1 appears to play a role in cell adhesion and the high levels present in cancer may be causally involved in metastasis. At present the main uses of CA 15-3 are in preclinically detecting recurrent breast cancer and monitoring the treatment of patients with advanced breast cancer.

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CA 15-3 antibody

Mouse monoclonal CA 15-3 antibody

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Price From: Price: €439.26

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Price From: Price: €439.26
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